NEUROTOXICITY RESEARCH文献大全第5页

MPTP-induced apoptosis in the retina of goldfish.
abstract：:Neuronal degeneration observed in the goldfish retina after MPTP administration, displays features of apoptosis, a physiological mechanism of cell death that occurs during development. The ultrastructural features of degenerating retinal neurons, that are seen in the inner nuclear layer two days after intravitreal MPT...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033264

authors： Villani L,Beraudi A,Giuliani A,Poli A

更新日期：2001-07-01 00:00:00
The possible role of one-electron reduction of aminochrome in the neurodegenerative process of the dopaminergic system.
abstract：:We present for discussion a possible molecular mechanism explaining the formation of reactive oxygen species involved in the neurodegenerative process of dopaminergic system in Parkinson's disease. This new hypothesis involves one-electron reduction of aminochrome to o-semiquinone radical, which seems to be the reacti...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033188

authors： Segura-Aguilar J,Metodiewa D,Baez S

更新日期：2001-04-01 00:00:00
The developing cholinergic system as target for environmental toxicants, nicotine and polychlorinated biphenyls (PCBs): implications for neurotoxicological processes in mice.
abstract：:During neonatal life, offspring can be affected by toxic agents either by transfer via mother's milk or by direct exposure. In many mammalian species the perinatal period is characterized by a rapid development of the brain - "the brain growth spurt" (BGS). This period in the development of the mammalian brain is asso...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033229

authors： Eriksson P,Ankarberg E,Viberg H,Fredriksson A

更新日期：2001-01-01 00:00:00
Dopamine induces cell death, lipid peroxidation and DNA base damage in a catecholaminergic cell line derived from the central nervous system.
abstract：:Dopamine can be autoxidized to superoxides and quinones. Superoxides can form hydroxyl radicals that are highly reactive with lipids, proteins and DNA leading to neuronal damage and cell death. We used a clonal catecholaminergic cell line (CATH.a) derived from the central nervous system to evaluate the effects of dopa...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033288

authors： Masserano JM,Baker I,Venable D,Gong L,Zullo SJ,Merril CR,Wyatt RJ

更新日期：2000-02-01 00:00:00
The neuroprotectant properties of glutamate antagonists and antiglutamatergic drugs.
abstract：:In the slowly progressive neurodegenerative disorders like Parkinson's disease and Alzheimer's disease very different neuronal populations undergo degenerative processes, although the cascades of cellular events leading to death are supposed to be similar. We suggest that the complex pattern of degeneration in Parkins...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033793

authors： Pedersen V,Schmidt WJ

更新日期：2000-01-01 00:00:00
Toxicity of dopamine and dopaminochrome on cultured cells.
abstract：:Cultured rat fibroblasts, monkey kidney tumor cells (line Vero) and murine neuroblastoma cells were exposed to dopamine or dopaminochrome in the presence and absence of ascorbic acid. Ascorbic acid is able to potentiate the toxicity of both dopamine and dopaminochrome for all the tested cells. The toxicity of dopamino...

journal_title：Neurotoxicity research

pub_type： 杂志文章

doi：10.1007/BF03033278

authors： Galzigna L,Zanatta L,Esposito N

更新日期：1999-12-01 00:00:00

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